AST/ALT Ratio
The AST/ALT ratio compares two liver enzymes by dividing your AST value by your ALT value. It is a calculated number rather than a directly measured one.
The ratio can add context that neither enzyme gives alone. Different liver conditions tend to shift AST and ALT by different amounts, so the balance between them can offer clues about the underlying pattern. Clinicians use it as one piece of a larger assessment, not a standalone verdict.
A higher ratio, where AST outweighs ALT, is sometimes associated with certain liver patterns, including alcohol-related liver strain or more advanced liver changes. It can also rise when AST comes partly from muscle. The ratio is suggestive at best and always needs interpretation alongside the actual enzyme values and your history.
A lower ratio, where ALT is relatively higher, is common and by itself is not a specific concern. It simply reflects the balance between the two enzymes.
There is no single target ratio to chase, since its meaning depends entirely on the accompanying enzyme levels and clinical picture. Your clinician is best placed to interpret what your ratio means for you.
Sources
Educational context only, not medical advice or a diagnosis. Reference ranges vary by lab, age and sex; always discuss your results with a clinician.