Mean Platelet Volume
Mean platelet volume (MPV) is the average size of your platelets. Newer platelets tend to be larger, so MPV offers a clue about how actively your bone marrow is producing them.
The size of your platelets can hint at whether your marrow is ramping up production or whether platelets are being destroyed or used faster than usual. MPV adds nuance to the platelet count when clinicians investigate a bleeding or clotting picture.
An above-range MPV suggests larger, often younger platelets, which can indicate your marrow is actively replacing platelets that are being consumed or destroyed. It can appear in certain platelet and inflammatory conditions and is interpreted alongside your platelet count.
A below-range MPV points to smaller platelets and can be seen when marrow production is reduced or in some inherited conditions.
A typical adult MPV runs roughly 7.5-11.5 femtoliters, varying by analyzer. It's most meaningful when read together with your platelet count and by your clinician.
Sources
Educational context only, not medical advice or a diagnosis. Reference ranges vary by lab, age and sex; always discuss your results with a clinician.