Library/Kidney/eGFR/23

eGFR of 23 mL/min/1.73m²What it means, and what usually happens next

23mL/min/1.73m² eGFR
Severely decreased (G4)
1530456090

An eGFR of 23 mL/min/1.73m² is in the 15 to 29 range KDIGO calls severely decreased (stage G4).

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eGFR23mL/min/1.73m²
Where it fallsSeverely decreased (G4)
The usual range90 or above (it drifts down with age)

What usually happens next

KDIGO advises care with a kidney specialist at an eGFR under 30.

Many medicines are dosed differently at this level, so every prescriber should know the number.

When an eGFR can read wrong

Most eGFRs are worked out from creatinine, which comes from muscle. A lot of muscle, creatine supplements, a big meat meal before the test or being dehydrated can make the eGFR read lower than your kidneys really are; very little muscle can make it read higher. A cystatin C based eGFR is the usual way to check.

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Questions

Is an eGFR of 23 mL/min/1.73m² normal?

An eGFR of 23 mL/min/1.73m² is in the 15 to 29 range KDIGO calls severely decreased (stage G4). The usual range is 90 or above (it drifts down with age).

Is an eGFR of 23 mL/min/1.73m² normal for my age?

eGFR falls slowly with age, so a value in the 60s or 70s is common in healthy older adults. What matters is whether it stays under 60 for more than 3 months, or comes with albumin in the urine.

Can an eGFR of 23 mL/min/1.73m² improve?

It can move: dehydration, a big protein meal or a hard workout before the test lowers it, and a repeat test when well hydrated often reads higher.

Worked out by LifeFrom from the KDIGO 2024 guideline, and not yet reviewed by a clinician. For your own understanding: only a lab test, read by your clinician, diagnoses anything.