Library/Electrolytes/Anion gap/1

Anion gap of 1 mEq/LWhat it means, and what usually happens next

1mEq/L Anion gap
Low
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An anion gap of 1 mEq/L is below the usual range on modern analysers.

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Anion gap1mEq/L
Where it fallsLow
The usual rangeabout 4 to 12 mEq/L on most modern analysers (8 to 16 on older ones); your lab's own range is the one to use

What usually happens next

The most common reasons are low albumin in the blood or a lab or calculation quirk; a repeat often reads normal.

If it stays low, your doctor may check albumin and, rarely, look for an abnormal protein (as in myeloma).

What a low anion gap usually means, and its common causes

When an anion gap can read wrong

The anion gap is worked out from sodium, chloride and bicarbonate, so any error in those moves it. Low albumin lowers it (by about 2.5 for each 1 g/dL drop), and labs use different ranges depending on their analyser.

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Questions

Is an anion gap of 1 mEq/L normal?

An anion gap of 1 mEq/L is below the usual range on modern analysers. The usual range is about 4 to 12 mEq/L on most modern analysers (8 to 16 on older ones); your lab's own range is the one to use.

Is an anion gap of 1 mEq/L bad?

Read it against the range on your report: modern analysers use about 4 to 12 mEq/L, older ones 8 to 16. A high gap with a low bicarbonate matters most.

Worked out by LifeFrom from Kraut and Madias's review and the usual lab ranges, and not yet reviewed by a clinician. For your own understanding: only a lab test, read by your clinician, diagnoses anything.