- 01Low desire is different from a body that won't respond
Libido is wanting sex. Erection problems, vaginal dryness and trouble reaching orgasm are about the body's response. They often travel together, but they have different causes and different treatments: erection tablets such as sildenafil help blood flow and do not increase desire.
- 02A low sex drive is only a problem if it bothers you
Sex drive varies a lot between people and across a life. Cleveland Clinic advises talking to a clinician when it bothers you or affects your well-being, not because it falls below some number.
A low sex drive (low libido) means feeling less interest in sex than you used to, and most of the time the cause is ordinary: stress, tiredness, the state of the relationship, low mood, alcohol or a medicine. 12 Life stages play a big part, from pregnancy and a new baby to menopause in women and slowly falling testosterone in men. 13 A smaller share comes from medical causes a blood test can check: low testosterone, a high prolactin (a pituitary hormone), an underactive thyroid or diabetes. 16
When to get help now
Low desire itself is never an emergency. These are.
LifeFrom can't examine you or assess a symptom. If something feels seriously wrong, trust that and get care rather than waiting on a test.
What counts as a normal sex drive?
There is no normal number. Cleveland Clinic puts it this way: “Everyone's sex drive is different, and it can change throughout your life.” 1 Desire rises and falls with health, age, stress, relationships and hormones. A drop is worth looking into when it bothers you or your partner, when it is new and unexplained, or when it comes with other symptoms such as tiredness, low mood or changes in your periods or erections. 1
Low desire or a body that won't respond?
Libido is the wanting. Arousal and function are the body's part: erections in men, lubrication and orgasm in women. The two get tangled, because sex that hurts or fails to work tends to kill desire over time, but they are not the same problem. 1 The MedlinePlus label for sildenafil, an erection drug, is blunt that it “does not cure erectile dysfunction or increase sexual desire.” 10 Telling a clinician which part changed first, the wanting or the working, points them toward the right causes.
Is it low desire, or a problem with the body's response?
What can cause it, most likely first
Ranked from most to least likely in adults in general. The order shifts with age, sex and history: menopause rises to the top for women in their late 40s and 50s, low testosterone for older men, and medicines for anyone who started one recently.
- 01Stress and relationship problems
Stress from work, family or daily life, and problems in the relationship such as a lack of trust or closeness, are among the most common reasons desire drops. 1 The NHS lists relationship problems, stress and anxiety first among its causes. 2 No blood test reads these; talking, and sometimes couples or sex therapy, does.
- 02Tiredness and poor sleep
Physical fatigue is one of the mental and physical factors Cleveland Clinic lists, and caring for a new baby is a classic combination of exhaustion and hormone change. 12 If you are worn out most days, the fatigue and can't sleep pages cover the causes and the tests for those.
- 03Medicines, including antidepressants and birth control
Antidepressants, antipsychotics, some blood pressure medicines and chemotherapy can lower sex drive, and so can some hormonal birth control (the pill, patch, ring, implant or injection). 12 The NHS lists low sex drive and trouble reaching orgasm as common side effects of SSRI antidepressants. 8 Opioid painkillers can lower testosterone in men. 3 Do not stop or change a medicine on your own; a prescriber can weigh the options.
- 04Depression and anxiety
Depression, low self-esteem and hopelessness can take desire with them, and anxiety does the same. 12 No blood test diagnoses depression; a clinician asks about mood, sleep and interest in things you used to enjoy. If low mood comes with thoughts of self-harm, call or text 988 now. 11
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- 06Pregnancy, a new baby and menopause
Hormones shift sharply in pregnancy, after birth and while breastfeeding, and the tiredness of a new baby adds to it. 2 Around menopause (usually between 45 and 55), estrogen falls, and “decreased interest in sex” and vaginal dryness with painful sex are common symptoms. 9 Hormone tests can support the picture, but menopause is usually recognized from age and periods.
- 07Low testosterone in men
Testosterone shapes libido in men, and low libido is listed first among the sexual symptoms of low testosterone. 3 Levels fall about 1% a year from the late 30s, and obesity, diabetes, opioids and pituitary problems can push them lower. 3 The Endocrine Society guideline says the diagnosis needs symptoms plus “unequivocally and consistently low” testosterone on repeated fasting morning tests. 4
Can be linked with Low testosterone
- Testosterone, total
- Below 300 ng/dL is usually called low in adult men, and it should be confirmed on a second morning sample because levels are highest in the morning and illness lowers them. 34
- Testosterone, free
- The share not bound to proteins; a low free testosterone can matter when total sits near the cutoff. The guideline bases diagnosis on low total and/or free testosterone. 4
- 08Thyroid problems
An underactive thyroid is one of the health conditions linked with a lower sex drive, often alongside tiredness, weight gain, feeling cold and low mood. 114 Nearly 5 in 100 Americans aged 12 and over have hypothyroidism. 14
Can be linked with Hypothyroidism
- TSH
- A high TSH (thyroid stimulating hormone) points to an underactive thyroid; it is the usual first thyroid test. See how to read your thyroid panel.
- Free T4
- A low free T4 with a high TSH fits an underactive thyroid; the thyroid panel guide explains the other patterns.
- 09Diabetes
In women with diabetes, nerve damage can lead to low sexual desire, vaginal dryness and painful sex. 7 Men with diabetes are more than 3 times as likely to develop erection problems and more likely to have low testosterone, especially if older and overweight. 7 See blood sugar explained for how the tests work.
- HbA1c
- A high HbA1c means blood sugar has been running high over recent months, the pattern linked with diabetes and with the nerve and blood vessel damage that affects sex. 7
- Glucose, fasting
- A high fasting glucose points the same way; it needs a fast beforehand. See blood sugar explained.
- 10High prolactin
Prolactin is a pituitary hormone; too much of it lowers sex drive in women and men, and in men it comes with low testosterone and erection problems. 6 In women it can also cause irregular or missing periods and milky nipple discharge. 6 The cause is often a prolactinoma, a benign pituitary growth, or a medicine such as some antipsychotics, blood pressure drugs, anti-nausea drugs or opioids. 6
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These are things a symptom like this can be linked with, not a diagnosis. Several can sit together, and a clinician who knows your history puts them in order for you.
Low sex drive in women
Women search for this far more than men, and Cleveland Clinic says low libido affects more women than men over a lifetime. 1 For women, desire is often tied to how the rest of life is going: sleep, stress, how the relationship feels, body image and whether sex is comfortable. 1 The hormone milestones carry a lot of weight. Pregnancy and the months after a birth, especially while breastfeeding, lower desire for many women, and the NHS suggests seeing a GP if sex drive has not returned to normal after pregnancy. 2 Around menopause, falling estrogen brings “decreased interest in sex or changes in sexual response” along with dryness that can make sex painful. 9
Hormonal birth control deserves a mention because it is easy to overlook: the pill, patch, ring, progestogen-only pill, implant and injection can all lower desire in some people. 1 Contraception changes are a conversation for your prescriber, since switching methods carries its own trade-offs. 2
Low sex drive in men
Men get the same everyday causes, and they are still the most common ones. 1 Low testosterone gets the attention because it is testable, and because low libido and erection problems are its most specific signs. 3 It is a diagnosis that takes care: the American Urological Association treats a man as testosterone deficient “only when they meet both criteria,” low levels and symptoms together. 13 A single low reading after a bad night, an illness or in the afternoon is not enough, which is why two morning samples are standard. 34
Can medicines cause a low libido?
Often. Antidepressants, especially SSRIs, are the best-known example: the NHS lists “problems with sex, such as low sex drive, finding it difficult to orgasm” among their common side effects, and notes that for some people these can carry on after stopping. 8 Blood pressure medicines, antipsychotics, opioids and hormonal contraception are the others to think about. 123 The NHS is firm that you should not stop an antidepressant suddenly; it suggests agreeing a plan with your doctor. 8 A prescriber can talk through the options.
Can depression cause a low sex drive?
Yes, and it runs both ways: depression lowers desire, and the medicines that treat it can too. 18 Losing interest in sex alongside losing interest in food, friends or hobbies, poor sleep and feeling hopeless for more than a couple of weeks is worth raising with a clinician on its own. If you have thoughts of harming yourself, call or text 988; the Lifeline is “available 24/7/365” and conversations are free and confidential. 11
The panel that checks these
If a clinician tests, the first round is usually total testosterone in men (fasting, in the morning, repeated if low), prolactin, TSH and HbA1c, because those read the medical causes that are treatable. 346 FSH and estradiol come in for women around menopause, and LH when a man's testosterone is low.
- FSHPregnancy, a new baby and menopause
- EstradiolPregnancy, a new baby and menopause
- Testosterone, totalLow testosterone in men
- Testosterone, freeLow testosterone in men
- LHLow testosterone in men
- TSHThyroid problems
- Free T4Thyroid problems
- HbA1cDiabetes
- Glucose, fastingDiabetes
- ProlactinHigh prolactin
LifeFrom doesn't sell blood tests. It reads results from any lab and helps you prepare for your own doctor; it doesn't diagnose.
Getting a useful test
- Say which changed first: desire, erections, dryness, pain or orgasm.
- Bring every medicine and supplement, with start dates, including birth control and anything bought for libido or testosterone. 112
- Testosterone is read from an early morning, fasting draw, and a result taken during or just after an illness can be misleadingly low. 34
- Prolactin can rise with some medicines, so tell the clinician everything you take; a high result is read with your medicine list. 6
- High-dose biotin can distort thyroid tests, most often making TSH look falsely low; mention it. 15
- One result is a snapshot; see why trends beat single readings.
What may help
Treating the cause is what helps most, and the NHS puts it plainly: “Treating the cause should help increase your sex drive.” 2 The everyday steps below have the best support.
Start with the everyday things- Protect sleep and recovery; tiredness is one of the commonest causes. 1
- Keep alcohol moderate; heavy drinking lowers desire. 1
- Talk to your partner, and consider couples or sex therapy; the NHS lists counselling for relationship difficulties as a treatment. 2
- Use a lubricant if dryness makes sex uncomfortable. 2
- Aim for a healthy weight and stay active; obesity is linked with low testosterone in men. 3
No supplement has good evidence for raising libido, so none is listed here. Products sold for sexual enhancement have been found to contain hidden drug ingredients, and the FDA warns they “pose a serious health risk and are not guaranteed to work.” 12 Supplements support general wellness. They don't treat the causes above, and if a test finds one, treating that comes first. If you take medicines, are pregnant or have a health condition, check with your clinician before starting anything.
Questions to ask your clinician
- Could any of my medicines or my birth control be lowering my sex drive, and what are the alternatives?
- Is this more likely low desire, or a problem with arousal, erections or pain?
- Should we check testosterone (in the morning, twice), prolactin, TSH or HbA1c?
- Could perimenopause or menopause explain this, and what are the options for dryness or pain?
- Would counselling or sex therapy help, and can you refer me?
This page is general education, not medical advice or a diagnosis. A low sex drive usually has more than one cause, and the clinician who knows your history, your medicines and your results is the one to sort them out with you.
Citations
- Cleveland Clinic. Low libido (low sex drive). Updated April 2025.
- NHS. Loss of libido (low sex drive).
- Cleveland Clinic. Low testosterone (male hypogonadism).
- Bhasin S, Brito JP, Cunningham GR, et al. Testosterone therapy in men with hypogonadism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.
- MedlinePlus Medical Encyclopedia. Hypogonadism. US National Library of Medicine.
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Prolactinoma.
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Diabetes, sexual, and bladder problems.
- NHS. Side effects: selective serotonin reuptake inhibitors (SSRIs).
- MedlinePlus Medical Encyclopedia. Menopause. US National Library of Medicine.
- MedlinePlus Drug Information. Sildenafil. US National Library of Medicine.
- 988 Suicide & Crisis Lifeline.
- US Food and Drug Administration. Sexual enhancement and energy product notifications (medication health fraud).
- American Urological Association. Evaluation and management of testosterone deficiency guideline (2018, validity confirmed 2024).
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Hypothyroidism (underactive thyroid).
- American Thyroid Association. Clinical Thyroidology for the Public: biotin and thyroid function tests. December 2018;11(12):3-4.
Educational context only, not medical advice or a diagnosis. Always discuss your results with a clinician.





