Absolute Neutrophil Count (Calculated)
The absolute neutrophil count, or ANC, is the total number of neutrophils per unit of blood, calculated from your white cell count and the neutrophil percentage. Neutrophils are the immune cells that form your first line of defense against many infections.
The ANC is one of the most important indicators of how well-equipped you are to fight off bacterial and fungal infections. It is closely watched in people receiving treatments that can lower white cells, such as chemotherapy. Because it is calculated, it depends on the accuracy of the counts it is derived from.
A high ANC often reflects your body responding to infection, inflammation, physical stress, or certain medications. It usually indicates an active immune response rather than a specific disease. Your clinician will interpret it alongside your symptoms and the rest of your blood count.
A low ANC, called neutropenia, means fewer neutrophils are available to fight infection, which can raise infection risk when it is markedly reduced. This can follow certain medications, infections, or marrow conditions and should be discussed promptly with your clinician.
Reference ranges vary by lab and situation; a markedly low ANC warrants timely medical attention. Use your report's range and discuss results with your clinician.
Sources
Educational context only, not medical advice or a diagnosis. Reference ranges vary by lab, age and sex; always discuss your results with a clinician.